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Interstitial Lung Disease

The term interstitial lung disease (ILD) refers to a collection of several lung disorders. The interstitium, a section of your lungs, is impacted by all interstitial lung disorders.

The interstitium is a network of tissue that runs across both lungs and resembles lace. It supports the alveoli, which are small air sacs found in your lungs. The interstitium is typically so thin that neither CT scans nor X-rays can detect it.

Overview


Interstitial lung disease comes in more than 200 varieties. The most common among them are:


Asbestosis: lung inflammation and scarring brought on by asbestos fiber inhalation

Blockages in the lungs' tiniest airways, known as bronchioles, are the result of bronchiolitis obliterans.


Black lung disease, or coal worker's pneumoconiosis: is a lung ailment brought on by coal dust exposure.


Chronic Silicosis: Is a lung condition brought on by inhaling the silica mineral.


Connective tissue-related pulmonary fibrosis: Some persons with connective tissue illnesses, such scleroderma or Sjögren syndrome, develop connective tissue-related pulmonary fibrosis, a lung condition.


Desquamative interstitial pneumonitis: Lung inflammation brought on by desquamative interstitial pneumonitis is more prevalent among smokers.


Familial pulmonary fibrosis: A accumulation of scar tissue in the lungs that affects a group of peple in a family  is known as familial pulmonary fibrosis.  

                                                       

Hypersensitivity pneumonitis: Intolerance Inflammation of the alveoli brought on by breathing in allergens or other irritants is known as pneumonitis.


Idiopathic pulmonary fibrosis: is an unidentified illness where scar tissue grows all over the lung tissue.


Sarcoidosis: is a condition that results in the formation of tiny clusters of inflammatory cells in organs like the lymph nodes and lungs.



Causes


Most interstitial lung diseases have no known cause.


Interstitial pneumonia can be brought on by bacteria, viruses, or fungus. Additionally, breathing in items that can irritate your lungs on a daily basis can cause ILD. These consist of.


  • Asbestos                                                                          

  • Bird proteins (from pigeons, chickens, or exotic birds, for example)

  • Dust from coal mining or other metal mining operations

  • Farming-related grain dust

  • Dust of silica

  • Talc

Although uncommon, some medications can result in ILD,

  • Nitrofurantoin is one example of an antibiotic.

  • Certain anti-inflammatory medications, such as rituximab

  • Bleomycin and other chemotherapy medications

  • Drugs for the heart, like amiodarone

Interstitial lung disease can affect anyone, but some factors can increase your risk like, 

  • Age. ILD is far more common in adults, although it can also strike children.

  • Autoimmune conditions such as scleroderma, rheumatoid arthritis, and lupus

  • Genetics of gastroesophageal reflux disease (GERD). Certain conditions are inherited by family members.

  • Smoking

  • Cancer therapy using radiation


Symptoms


Numerous symptoms can arise from lung injury, inflammation, and oxygen deprivation in people with interstitial lung disease. These consist of,


  • Breathing difficulties, particularly after exercising or climbing stairs

  • Strange noises when you breathe 

  • Weariness and a dry cough

  • Discomfort or soreness in the chest, clubbing of the fingers or toes

The severity of the symptoms can vary, and they might resemble those of other respiratory disorders or other health issues.



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