Overview

Nephrotic syndrome may develop when the kidneys' filtering units are compromised. This damage lowers the amount of protein in your blood by allowing protein that is typically contained in the plasma to seep into the urine in significant proportions. A portion of the fluid seeps out of the bloodstream into your tissues, creating swelling known as oedema, because the protein in your blood helps retain fluid in the bloodstream.

When you first get up in the morning, the swelling could be particularly noticeable around your eyes and in your legs after you have been standing. Eventually, the swelling in your legs could not go away and might even spread to other areas of your body. You may notice more foaming urine than usual.

Causes

Nephrotic syndrome can be caused by a variety of illnesses. These are the most prevalent (for additional details, click on an illness):- 

• Minimal Change Nephropathy 

• Renal Vein Thrombosis 

• Segmental and focal glomerulosclerosis, MPGN, or membrane-proliferative glomerulonephritis, 

• Diabetes 

• Amyloidosis

Symptoms

Nephrotic syndrome symptoms include,

• Frothy and foamy urination 

• Sudden weight loss 

• Overall malaise, or feeling sick 

• Oedema, or fluid retention or swelling, especially in the legs, eyes, and belly area 

• Muscular atrophy 

• Stomach pain and lightheadedness after rising from a seated or supine posture (orthostatic hypotension). 

• Decrease in appetite  

• Exhaustion

Ayurvedic View

Mutravaha sroto vikara- due to aggravated doshas, namely vata, pitta, kapha, after entering the mutravaha srotas (urinary system), disrupts normal functioning of the urinary system, which is nephrotic syndrome. The Ayurveda way of approach is to bring dosha back to prakruta awastha (balance state), improve the renal health and reduce the associated symptoms occurring in this disease.